To compute skews, the input sequence is scanned with a sliding window, and the requested parameter is calculate
for each window. The data is shown in a graph.
G+C %
The porcentaje of G+C is computed
GCskew
For each window, (GC)/(G+C) is computed, where G and C are the number of ocurrences for each nucleotide
ATskew
For each window, (AT)/(A+T) is computed, where A and T are the number of ocurrences for each nucleotide.
KETOskew
For each window, (G+CAT)/(G+C+A+T) is computed, where A, C, G and T are the number of ocurrences for each nucleotide.
Oligoskew
For each window, frecuencies for all nucleotides with selected length is computed.
Those frecuencies are compared to frecuencies obtained from the complete sequence.
When comparing both frecuencies, Pearson distance is computed, as described
here.
